pandas add header to existing dataframe

32
Cov = pd.read_csv("path/to/file.txt", sep='\t')
Frame=pd.DataFrame(Cov.values, columns = ["Sequence", "Start", "End", "Coverage"])
Frame.to_csv("path/to/file.txt", sep='\t')
Cov = pd.read_csv("path/to/file.txt", 
                  sep='\t', 
                  names=["Sequence", "Start", "End", "Coverage"])

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