>>> df = pd.DataFrame({"A": [1, 2, 3], "B": [4, 5, 6]})
>>> df.rename(columns={"A": "a", "B": "c"})
a c
0 1 4
1 2 5
2 3 6
df_new = df.rename(columns={'A': 'a'}, index={'ONE': 'one'})
print(df_new)
# a B C
# one 11 12 13
# TWO 21 22 23
# THREE 31 32 33
print(df)
# A B C
# ONE 11 12 13
# TWO 21 22 23
# THREE 31 32 33
df.rename({0: 'links'}, axis=1, inplace=True)