subtract one list from another python

[item for item in x if item not in y]

# Subtract list1 from list2 (find only items not in both lists)
list1 = [2, 2, 2]
list2 = [1, 1, 1]
difference = []   # initialization of result list

zip_object = zip(list1, list2)

for list1_i, list2_i in zip_object:
    difference.append(list1_i-list2_i) # append each difference to list

print(difference)